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"Hy's law"
Summary: GLP-1 medications slow gut motility and gastric emptying, leading to harder stools and constipation, which can be managed through increased dietary fibre, adequate hydration, regular physical activity, and appropriate laxative use when necessary
Therefore, microbiota-related conclusions should be interpreted cautiously, and future sequencing-based studies are recommended
These include certain aphrodisiac effects and a mild positive fat-mobilizing effect
Glucagon-like peptide 1 and its analogues Therapy with most glucagon-like peptide 1 (GLP1) analogues in patients with T2DM reduced the rate of major adverse cardiac events in cardiovascular outcome trials 79,91
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