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Research protocols investigate how senescent cell elimination affects stem cell function, tissue regeneration capacity, and organ homeostasis, providing insights into mechanisms of aging and potential interventions for age-related diseases

Capsaicin increases ACSL4 mRNA and protein levels in U87-MG and U251 cells while reducing GPX4 mRNA and protein levels, thereby decreasing intracellular GPX4 and GSH levels, increasing ACSL4 levels, and exhibiting concentration-dependent anti-proliferative effects [82]

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J Biol Chem 270, 23202326 (1995)