The safety concern: Early reports suggested GLP-1s might increase suicidal ideation
Increases Vasodialation
[1] If you experience new or worsening anxiety, low mood, or suicidal thoughts whilst taking a GLP-1 medication, seek urgent help immediately
Compared with unexposed pregnancies, the GLP-1 RA-exposed group had a higher risk for excess gestational weight gain (risk ratio, 1.32), greater mean birth weight percentile (58.4 versus 54.8 percent), and a higher risk for preterm delivery, gestational diabetes, and hypertensive disorders of pregnancy (risk ratios, 1.34, 1.30, and 1.29, respectively)
Marijuana withdrawal symptoms often begin within the first few days after stopping use and can continue for several weeks or even months, for some people