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14 Discussion While the herbal formulations and their active compounds, standalone or in combination, have demonstrated robust in vitro efficacy, translation to in vivo and clinical settings remains variable, and oftentimes a large therapeutic barrier

In the case of the ACL, mechanobiology studies can reveal how mechanical loading patterns affect cellular activities such as proliferation, differentiation, and matrix production

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Fricker G, Kromp T, Wendel A, Blume A, Zirkel J, Rebmann H, Setzer C, Quinkert R-O, Martin F, Mller-Goymann C