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Black or tar-like stool (melena): This colour often indicates bleeding in the stomach or upper small intestine, where the blood has been digested

2) Diarrhea - early on, I did have some mild diarrhea

Adding 0.1% sodium ascorbate as a sacrificial antioxidant and 0.01% EDTA to chelate trace metal catalysts further extends shelf life pharmaceutical formulations use degassed PBS with these additives plus nitrogen headspace displacement to achieve 2830 day stability at 4C

A reduced appetite is commonly noticed within the first week, which is one of the earliest signs that the medication is beginning to work