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Time-Dependent Relationship Between Mucosal GSH Levels and Colitis Development To determine the role of GSH depletion induced by TNBS+ethanol on the appearance of injury, we determined the time dependent regulation of mucosal GSH levels and onset of injury in rats treated with TNBS+ethanol during the induction of colitis

GSH depletion by BSO treatment did not significantly increase caspase 3 activity (data not shown)

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