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Specific microbiota enhances intestinal IgA levels by inducing TGF- in T follicular helper cells of Peyers patches in mice
SA node effect shud be right from beginning, why sympathetic effect on SA shows after a lag at 24 weeks, also if it's as shown in graph peaks after hiatus is this due to drug induced Increased basal metabolic rate(obvioous will be increased HR)
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Lancet 2020;396:122349
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