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Immediate medical attention is warranted if you develop concerning symptoms, including: Severe or persistent abdominal pain, which may indicate pancreatitisa rare but serious adverse effect of GLP-1 receptor agonists [1] [3] Severe upper abdominal or right-upper-quadrant pain, fever or jaundice, which may indicate gallbladder disease Persistent nausea, vomiting, or diarrhoea leading to dehydration or inability to keep fluids down Signs of hypoglycaemia (if taking concurrent insulin or sulphonylureas)tremor, sweating, confusion, palpitations Unexplained weight gain, particularly if rapid or associated with oedema New or worsening visual symptoms, especially if you have pre-existing diabetic retinopathy A comprehensive medication review should be arranged if you are taking multiple medications, as drug interactions or weight-promoting agents may require adjustment

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By managing stress through techniques such as mindfulness, yoga, or other relaxation methods, individuals can help regulate cortisol levels and support weight loss efforts

Also, a significant delayed (T4) decrease in blood GLP-1 concentration was observed under oral cannabis, but not other conditions (Fig

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