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Support around access to food is a particular issue due to impaired satiety and, because of this, people with PWS eat excessive amounts of food (hyperphagia)
Look for the FSA/HSA eligible label on applicable products
Menstrual Cycle Effects Weight loss of 20%+ affects the menstrual cycle in most women
Vomiting, diarrhea, constipation, indigestion, abdominal discomfort, and decreased appetite have also been reported in retatrutide research
Jan 16, 2026 11 min read IN THIS ARTICLE KEY TAKEAWAYS Weight loss includes both fat and muscle loss, not just fat
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