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Instruct patients to inform healthcare providers prior to any planned surgeries or procedures if they are taking RYBELSUS Adverse Reactions Most common adverse reactions (incidence 5%) are nausea, abdominal pain, diarrhea, decreased appetite, vomiting and constipation Drug Interactions RYBELSUS stimulates insulin release in the presence of elevated blood glucose concentrations

GLP-1 medications mimic this hormone resulting in lower blood sugar , reduced appetite, and slower digestion of food

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Most GLP-1 drugs, like FDA-approved Ozempic and Wegovy, are injections