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After the reaction was completed, an appropriate amount of a mixed solution of acetic anhydride and pyridine (volume ratio: Ac2O/Pyridine=7/6) was added to block the reaction for 5 h or more, following washing three times with DMF
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In the U.S., combined prescriptions for these drugs jumped by over 510% between late 2023 and mid-2025, with 13.5 million people actively using them
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