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Retatrutidedelivers up to 22.6% weight loss in late-stage clinical trials In the second trial, adults with severe obesity and established cardiovascular disease, with or without diabetes, lost an average of up to 22.6% of their body weight, or 55.8 pounds, after 80 weeks

Its liquid nasal format enables precise volumetric handling for experimental protocols requiring peptide administration via mucosal surfaces or simulation thereof

DOI: 10.1038/s41467-017-01114-1 Formulation strategies for therapeutic peptide stability pH, ionic strength, co-solvency

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Human studies are very limited