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Holistic Health Assessment: Effective weight loss is more than a prescription

Improved Insulin Sensitivity Since berberine focuses heavily on insulin sensitivity via AMPK, it might complement the appetite-suppression effects of semaglutide

Supporting gut barrier integrity: Some probiotics, like Akkermansia Probiotic, may help support the gut barrier and the body's response to everyday oxidative stress

Orlistat works by reducing fat absorption rather than affecting appetite hormones, but it's important to note that it commonly causes gastrointestinal side effects (including steatorrhoea and urgency) and is contraindicated in chronic malabsorption conditions and cholestasis