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Also, DPP4 inhibition by sitagliptin or vildagliptin modulated the disturbed autophagy responses in CV disease (LC3II and P65 levels) and vildagliptin enhanced mitochondrial fusion (increased mfn-2 level)

Levels of PEA in hypothalamus (HYP) and cerebellum (CER) are also significantly increased when compared to vehicle control within brain region

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The FDA has also issued an alert on dosing errors with compounded semaglutide