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We aimed to investigate the association of SNPs in the incretin-related genes (GCG, GLP1R, DPP4, PCSK1, GIP and GIP1R) on the treatment effects of saxagliptin
However, for researchers, it's a key variable to monitor, as it can temporarily affect weight and measurements
In patients who already produce normal or elevated levels of endogenous GLP-1, flooding those same receptors with long-acting agonists may push a finely tuned system past its adaptive range
Regardless of which GLP-1 pathway compound you and your healthcare provider eventually discuss, the underlying genetic architecture is still relevant
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