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GLP-1 receptor agonists (GLP-1 RAs), primarily developed for their metabolic effects 68 , demonstrated neuroprotective activity in preclinical models over two decades ago 9 with subsequent studies revealing anti-inflammatory effects in both central and peripheral tissues 10
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In vitro chondrogenic differentiation assay For chondrogenic differentiation in high-density pellet cultures, 2.5 10 5 of BMSCs were centrifuged to form a pellet
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