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Results Participants with HFpEF and higher baseline BMI were younger and more likely to be female and White, with greater WC and WHR compared with those with lower BMI (Table 1)
Effects of Liraglutide on Heart Rate and Heart Rate Variability: A Randomized, Double-Blind, Placebo-Controlled Crossover Study
Additionally, OS disrupts liver activity, promoting increased insulin resistance, which in turn inhibits lipolysis in adipose tissue
The scenario where adding phentermine makes the strongest case is this: a patient on maximum tirzepatide dosing for at least 6 months, with a documented weight loss plateau lasting 8 or more weeks, who has optimized diet, exercise, sleep, and stress management, and whose provider has ruled out medical causes for the plateau (thyroid dysfunction, medication interactions, fluid retention)