262, 263 Andersen, L
If you have type 2 diabetes and your HbA1c remains above target (typically above 7.0%) despite being on a full dose of metformin (1,500-2,000 mg daily), adding tirzepatide is one of the most effective next steps available

When to speak to your GP Contact your GP or rheumatologist if you experience: A significant RA flare after starting Wegovy or changing dose Persistent nausea or vomiting that affects your ability to take oral RA medications consistently New or worsening joint symptoms that dont follow your usual flare pattern Dehydration symptoms (dark urine, reduced urine output, dizziness), particularly if you take methotrexate, which requires adequate hydration for kidney clearance Significant weight loss that might affect your RA medication dosing Stomach pain or GI symptoms that are worse than expected, especially if youre taking NSAIDs or corticosteroids alongside Wegovy Feelings of low mood, anxiety, or being overwhelmed by managing your condition Frequently asked questions Is Wegovy safe with rheumatoid arthritis
With the launch of Zepbound, those requiring the medication for weight management should have increased access
But as semaglutide prescriptions increased, anecdotal reports of reduced drinking became common