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In vitro experiments demonstrated that agrin treatment significantly downregulated PDGFR and claudin-5 expression in a blood-brain barrier co-culture model comprising human brain microvascular endothelial cells and pericytes, suggesting that agrin may induce pericyte death and impair the integrity of the blood-brain barrier

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In contrast, restoring SAA metabolism alleviated the tumor phenotype resulting from HNF4 deficiency

Alcohol earlier in the evening, or skipped, since it can fragment sleep

Factors Influencing Bioavailability Pharmaceutical preparation the way in which a drug is formulated affects its rate of absorption