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The generation of oxygen free radicals is mainly related to incomplete reduction processes in redox reactions, specifically under conditions of active cellular metabolism, inflammation, or external stress, where their production increases significantly (Albano et al., 2022), (Da Silva et al., 2023)
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The antioxidant role of GSH GSH is implicated in several functions, including antioxidant defense with reduction of oxidative stress and maintenance of redox balance, metabolic detoxification from xenobiotics and exogenous compounds, cell cycle regulation, and immune system modulation, as well as fibrogenesis ( Its main role is to shield cellular macromolecules from endogenous and exogenous reactive oxygen species (ROS) and nitrogen ones