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As a result, type 2 diabetes patients exhibit an increased susceptibility to CVD, with a two to four times greater risk than non-diabetic counterparts
Moreover, a phase Ib clinical trial indicated that ADI-PEG20 combined with the PD-1 antibody pembrolizumab exhibited good tolerability and safety in treating patients with advanced solid tumors [282]
(2021) Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2(R1441G) mice
Women with HRS had a similar sCr than men in our analysis, which may be correlated with lower GFR and explain some differences in survival
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