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Because rodents have a higher density of GLP-1 receptors in thyroid C-cells, regulators issued boxed warnings about potential medullary thyroid carcinoma risk
The Specialist Pharmacy Service (SPS) and NHS practice guidance advise that when a GLP-1 receptor agonist is introduced, any DPP-4 inhibitor should generally be discontinued due to the mechanistic overlap and lack of additive benefit
It helps with energy and nerve health
Weight loss of 12 pounds per week is considered safe and healthy
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