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Kishimoto, A., Komiyama, M., Wada, H., Satoh-Asahara, N., Yamakage, H., Ajiro, Y., Aoyama, H., Katsuura, Y., Imaizumi, A., Hashimoto, T., Sunagawa, Y., Morimoto, T., Kanai, M., Kakeya, H., Hasegawa, K.: Efficacy of highly bioavailable oral curcumin in asymptomatic or mild COVID-19 patients: a double-blind, randomized, placebo-controlled trial
For the placebo arm participants were started on: 1 metformin, 2 dapagliflozin (Supplementary Table 4)
It also suppresses pro-inflammatory cytokines, reducing inflammation by regulating multiple cellular pathways, which is a major contributor to age-related decline or diseases
Thus, for each cycle, people with type 2 diabetes are at risk for MI, stroke, HF, ESKD and death, with the number experiencing each event in the cycle being tracked
After 72 weeks, participants taking 5mg per week lost 15% of their body weight on average, with many dropping over 20% at the highest dose of 15mg
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