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doi: 10.1038/s41591-024-03018-2
Key trials include TRIUMPH-1 (obesity without diabetes, primary weight loss endpoint at 72 weeks), TRIUMPH-2 (obesity with type 2 diabetes), and TRIUMPH-CVOT (cardiovascular outcomes in adults with overweight or obesity and established cardiovascular disease, mirroring the SELECT trial design)
Contamination and sterility concerns: Vials not produced under regulated manufacturing standards may contain microbes, endotoxins, or particulates leading to infection or systemic reactions
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