Andrea Corona Altimmunes GLP-1 drug shows positive results for alcohol use disorder On Tuesday, Altimmune announced topline data from their Phase 2 RECLAIM trial showing that pemvidutide, an investigational balanced glucagon/GLP-1 dual receptor agonist, significantly reduced the number of heavy drinking days compared to placebo in patients with moderate to severe alcohol use disorder
Evidence for the presence of L-arginine-nitric oxide pathway in human red blood cells: relevance in the effects of red blood cells on platelet function
3.4 Helicobacter pylori Helicobacter pylori ( H.p ) infection exerts its impact on the microecology starting from the oral cavity, which serves as a significant reservoir in sites such as dental plaque, carious lesions, and root canals, potentially acting as a source for gastric infection and transmission ( H.p can co-localize with and utilize the biofilm formed by S.m , creating an environment favorable for the proliferation of cariogenic bacteria (Zhang et al., 2018
BMC Cancer 2022 Jul 2;22(1):724
However, the limited bioavailability of glutathione due to rapid degradation hinders its delivery to the lens