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Nevertheless, studies on sepsis have led to improved knowledge useful for the development of future therapeutic targets

The peptide inhibits nuclear factor-B (NF-B) activation, a master regulator of inflammatory gene expression, while simultaneously activating peroxisome proliferator-activated receptor- (PPAR-), which promotes inflammatory resolution

GHK-Cu provides broader systemic benefits and strong mechanistic rationale but requires accepting the limitations of its research compound status

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