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Nausea, vomiting and diarrhea are common and can be severe enough to require dose adjustments
When NSBSO is reduced by GSH, the disulfide bond of NSBSO will break and NSBSO will then be converted to Nap- D F D FY-thiol and this process can be detected by liquid chromatography-mass spectrometry (LCMS) analysis (Additional file 1: Fig
Similarly, H7, A8 and F12 of GLP-1 interact with E 364 and F 367 of TM6 of GLP-1R, whereas, Igl2 of SR18 forms hydrophobic interactions with F 367
Seek immediate medical attention for severe dizziness with loss of consciousness, chest pain, neurological symptoms, or severe abdominal pain
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