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Limited clinical data hinder confident conclusions despite positive findings in animal models
The overall safety profile looked similar to that of other GLP-1 medicines
Important context: While worsening heart failure events were meaningfully reduced, cardiovascular deaths were numerically higher in the tirzepatide group at 2.2% versus 1.4% in the placebo group
You may notice some weight loss after about 4 weeks of taking Topamax
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