step 6 semaglutide Efficacy and safety of once-weekly 2·4 mg versus placebo in people with obesity and prediabetes (STEP 10): a randomised, double-blind, placebo-controlled, multicentre phase 3 trial The Potential of Semaglutide Once-Weekly

The largest psychiatric meta-analysis to date 80 randomized controlled trials, over 107,000 patients also found significant improvements in restrained eating and emotional eating with GLP-1 medications compared to placebo ( Pierret et al., JAMA Psychiatry, 2025 )

Tier 3: Non-preferred brand-name drugs

Hypoglycaemia risk requires consideration, particularly in patients with type 2 diabetes taking GLP-1 medications alongside insulin or sulfonylureas

If the drug does something more, on inflammation and the immune system, then even lean women might benefit

Our medical professionals begin with a detailed evaluation of your health, including medical history, allergies, and any liver or kidney concerns, to ensure your suitability for Ozempic