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The pharmacotherapy changes the biology and when you do that, people can move into a lifestyle change that is sustainable and feels easy to do. CV effects to be determined The data from the STEP program indicate use of semaglutide 2.4 mg should lead to long-term reductions in clinical cardiovascular events and reductions in long-term medical costs, but future studies will need to better define and quantify these effects, Lavie said in an interview
The current analysis showed consistent reductions with semaglutide in the risk of MACE versus placebo across baseline eGFR and UACR subgroups, which is in line with a meta-analysis that evaluated CVOTs showing that GLP-1RAs reduced the risk of MACE versus placebo, regardless of baseline eGFR [7]
The liver fat in these people went up by 86%, okay
Dietary quality matters as much as quantity when taking these medications
They also slow gastric emptying (producing feelings of fullness) and trigger feelings of satiation in the brain
