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Under physiological conditions, astrocytes support synaptic transmission by efficiently clearing glutamate via excitatory amino acid transporters (EAAT)1/2 106 , converting it into glutamine and supplying lactate to neurons through aerobic glycolysis 107

Generally, smaller nanoparticles (e.g., those in the 3-5 nm range) are more readily absorbed by roots and exhibit greater mobility throughout the plant vascular system (Khan et al., 2022)

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These effects typically emerge within the first 4-8 weeks of consistent use, with continued improvements over 6-12 months