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In both studies, from a mean baseline body weight of 96.7 kg, and 85.6 kg, respectively, after randomization there were corresponding mean reductions of 1.4 kg, and 1.6 kg in the SYMLIN treatment group compared to mean increases of +0.3 kg, and +0.1 kg in the placebo treatment group

GLP-1 Weight Management $70 per month .25 mg, .5 mg, 1 mg, 2 mg *This estimate derives from Novo Nordisk's Phase 3 clinical trial results which showed 14.9% average weight loss over 68 weeks among people utilized a maximum tolerated dose of 2.4 mg once-weekly

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Because fatty liver disease often improves with weight reduction and better insulin sensitivity, retatrutide is also being explored for liver-related outcomes such as liver fat content and inflammation markers