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Chronic inflammation and lipid accumulation in the liver, driven by obesity, activate TGF- signaling pathways, promoting hepatic fibrosis and metabolic dysregulation

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This microbial-endocrine crosstalk creates either vicious or virtuous cycles: PCOS-associated dysbiosis worsens hormonal imbalance

Transcriptional Regulation of Genes Encoding Glycolytic-Enzymes by Hypoxia-Inducible Factor-1