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FIGURE 3 PEROXIREDOXINTHIOREDOXIN REDOX CYCLE Peroxiredoxins constitute a family of thiol-specific peroxidases that rely on thioredoxins (Trxs) as the hydrogen donor for the reduction of H 2 O 2 and lipid hydroperoxides ( 2 O 2 produced by the mitochondrial respiratory chain

The suggested dithiol mechanism was based on experiments at a single substrate concentration that required more than 8 h for redox equilibration in the presence of 0.5 M glutaredoxin with or without 1 M GSH

We provide specific recommendations based on your treatment protocol and sensitivity

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