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The persistent activation of NMDAR by Hcy and MMA leads to prolonged excitotoxicity, impairs hippocampal function, and contributes to cognitive deficits (Poddar and Paul, 2009)

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The most common ones is nausea

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Why Gradual Escalation Matters for Safety The rationale behind any phased approach to treatment comes down to how the body adapts over time

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"They're always told 'diet and exercise,' and they're discouraged," Oden said

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Basic & clinical pharmacology & toxicology , 118 (1), 7076

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