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While results vary, GHK-Cu is often included in age-management skincare strategies for this reason
J Clin Endocrinol Metab 103(1):288294
GHK-Cu acts as a repair signal
If low B12 damages this sheath, nerve signals can misfire, leading to symptoms like tingling, numbness, or that awful pins and needles feeling
Combining compounds multiplies the number of potential side effects at play, and stacking unapproved research chemicals without medical supervision carries meaningfully more risk than using a single compound on its own
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