As complex, multifactorial diseases influenced by genetic and environmental factors, they typically have a slow onset, with patients often testing positive for autoantibodies years before showing any clinical signs or symptoms (79)
Disturbances in GSH homeostasis have been implicated in neurodegenerative disorders, liver disease, cystic fibrosis, pulmonary and cardiovascular diseases, as well as the chronic age-related diseases and the aging process itself.Recent data also suggests it plays a role in metabolic and inflammatory diseases such as multiple sclerosis, the metabolic syndrome, and diabetes, at least in part by influencing the effect of multiple environmental toxins, an underappreciated yet surprisingly significant association
Together they map the neuroprotective peptides as a group so you can reason about any single agent against the others, and against the limits of the data
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Stem Cells (2016) 34(2):34656