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1 Introduction Kidney transplantation (KT) is the preferred treatment for patients with end-stage renal disease (ESRD), offering superior survival and quality of life compared to dialysis ( PTDM was first reported in the 1960s ( The pathophysiology of PTDM is not fully understood but shares similarities with type 2 diabetes mellitus (T2DM), such as insulin resistance and impaired insulin secretion
& Heath, A
Romanucci V, D'Alonzo D, Guaragna A, et al
Other arginase inhibitors, including 2(S)-amino-6-boronohexanoic acid, effectively reduce hydroxyproline accumulation and reverse allergen-induced fibrosis [139]
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