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They joined prior risk factors such as hearing loss, hypertension, smoking, obesity, depression, physical inactivity, diabetes, excessive alcohol use, traumatic brain injury, air pollution, social isolation, and lower educational attainment

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry

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Gastrointestinal effectsparticularly nausea, vomiting, diarrhea, and constipationaffect 40-50% of patients, especially during dose escalation

95% CI, 1.36-1.42), and semaglutide (ROR, 3.00