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To put this in perspective, the antihypertensive medication lisinopril typically reduces systolic blood pressure by 8-10 mmHg
This is particularly useful for high-protein meals where incomplete digestion of sulfur-containing amino acids is a major contributor to hydrogen sulfide production
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Mechanistically, we show that, upon GSH depletion, the liver tissue induces the expression of target genes associated with the antioxidant transcription factor NRF2
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