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Description

Unlike phosphodiesterase inhibitors, which act peripherally, PT-141 exerts its effects centrally through the hypothalamus, influencing pathways associated with sexual arousal and behavior

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PMID 3257264

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doi: 10.1016/j.dsx.2020.03.009 35 NicolauJPujolATofeSBonetAGilA

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[11] These agents bind to GLP-1 receptors expressed throughout the body, including pancreatic beta cells, the gastrointestinal tract, and central nervous system regions involved in appetite regulation

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