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The patients who benefit most are those in steep deficits (1,2001,400 calories daily for women, 1,6001,800 for men) who present with elevated liver enzymes or fatigue despite adequate macronutrient intake

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- between 30 and 34.9: yes, if you have diastolic heart failure (also called heart failure with preserved ejection fraction), uncontrolled high blood pressure (also called hypertension), chronic kidney disease at stage 3a or higher, prediabetes, have had a heart attack, have had a stroke, or have blocked arteries in your legs or arms (peripheral artery disease)