This is life and death stuff so they override most other inputs
M.Citrinin affects the oxidative metabolism of BHK-21 cells.Cell Biochem and Function,1995 142
The main cerebral target for THC is type-1 cannabinoid receptors (CB1R), which are widely expressed in the brain and regulate various functions including neurotransmitter release, neuro-astroglial communication, and cellular bioenergetic processes [29,30,31,32]
The event rates ranged from 0.7 to 1.3 per 1,000 patient-years with the DPP-4 inhibitors and from 0.3 to 1.7 per 1,000 patient-years with the comparators
However, the main challenges in diseases related to neurodegeneration are defining optimal biomarkers for diagnosis and identifying biomarkers for assessing neuroprotection in humans