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It is intriguing that both recombinant IGF-1 (rIGF-1) and viral vectors encoding IGF-1 treatment could promote hepatoprotective activities in liver injury animal models and cirrhotic patients 11,12,13,14,15
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In the context of CKD, iron deposition is accompanied by the increased expression of iron input proteins (ZRT/IRT-like proteins, ZIP14 and ZIP8) or the decrease in FPN1 expression, indicating that iron accumulation may be triggered by increased iron uptake or insufficient iron efflux (Fig
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The higher effective dose from injection translates to more pronounced biological effects
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