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In the rabbit, higher doses of empagliflozin resulted in maternal and fetal toxicity at 700 mg/kg/day, or 139-times the 25 mg maximum clinical dose

Nearly every pharmacologic class carries theoretical or demonstrated risk in this population, and most prescribing recommendations are based on pharmacokinetic data and expert opinion rather than real-world pharmacoepidemiologic data or clinical trials

Additionally, egg yolk antioxidant levels increased, which reduced lipid peroxidation

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They have emerged as a promising treatment option for NAFLD due to their ability to aid in weight loss, improve insulin sensitivity, and reduce liver fat content