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Understanding that continued medication use will likely be necessary helps frame expectations appropriately

Presented for research literature review only Arendt J (2007)

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Of note, on the basis of epigenetic modification, another study contextualized the significance of lactate-promoting effects on histone H3K18 lactylation in association with histone H3K9 acetylation in UC management, by increasing MCT-induced macrophage lactate uptake, suppressing NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activation, and reducing macrophage pyroptosis induced by caspase-1 expression [129]

Rather, this lethal process is centered on the iron-dependent, oxidative destruction of membrane lipids