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[51] Diagnosis [edit] According to one review: "At present, no 'gold standard' test exists for the diagnosis of vitamin B 12 deficiency and as a consequence the diagnosis requires consideration of both the clinical state of the patient and the results of investigations." [52] The vitamin deficiency is typically suspected when a routine complete blood count shows anemia with an elevated mean corpuscular volume (MCV)

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Each lot is a synthetic pentadecapeptide corresponding to the 15-residue sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (GEPPPGKPADDAGLV), assembled by solid-phase peptide synthesis and purified to not less than 98% by reversed-phase HPLC, with lot-specific results documented on the Certificate of Analysis available on request

doi:10.2174/1570159x13666160502153022

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