First focus on the procedure itself, the true recovery risks, nutrition, activity restrictions, and follow-up
In severe osteoarthritis, the limiting problem is often structural joint degeneration
It's worth being realistic here: Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals)
It keeps injection volumes small enough for subcutaneous delivery while remaining measurable on an insulin syringe
For example, during Pseudomonas aeruginosa infection, butyrate modulates the maturation and effector functions of neutrophils, thereby influencing their recruitment and bactericidal capacity in the lungs and exerting complex regulation of the immune response (53)