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The medical rationale for weight loss in people with obesity is that obesity is a disease associated with a significant increase in mortality and many health risks, including type 2 diabetes mellitus, hypertension, dyslipidemia, and coronary heart disease

Countries in Sub-Saharan Africa, the Middle East, and Latin America will be particularly affected by this surge

Increasing proportions of all prescribed pharmaceuticals are excreted into sewage and treated in waste water treatment plants

doi:10.1016/S0140-6736(19)31149-3

This assessment should include a detailed history of symptom onset, frequency, severity, and relationship to medication initiation or dose changes