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Abbreviations CVOTs: Cardiovascular outcome trials DPP-4 inhibitors: Dipeptidyl peptidase-4 inhibitors GLP-1RA: Glucagon-like peptide-1 receptor agonists SGLT-2 inhibitors: Sodium-glucose cotransporter 2 inhibitors MACE: Major cardiovascular events RR: Risk ratio HHF: Hospitalization for heart failure References IDF Diabetes Atlas 2021 10th edition
The comparison is useful for understanding treatment options, but calling Toujeo a GLP-1 would be like calling aspirin an antibiotic because both come in pill form
Monotherapy-Dr Prabhat Ranjan The combination therapy of metformin and GLP-1 receptor agonists (GLP-1 RAs) demonstrates superior safety over monotherapy, while revealing novel adverse events and demographic-specific risk patterns, a large-scale pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) has reported
These medications are not recommended for patients with certain types of thyroid cancers, pancreatitis, gallbladder disease, hypoglycemia, decreased kidney function, or who are pregnant
Ozempic was originally developed for managing type 2 diabetes but has shown significant promise for weight management as well
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